Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
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In the standard 80mg presentation the split is GHK-Cu 50mg, KPV 10mg, BPC-157 10mg, and TB-500 10mg
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A clinical study treating crow's feet with GHK-Cu formulations showed substantial wrinkle reduction after 12 weeks, with skin biopsies confirming increased collagen in the upper dermis