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NNMT is a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, spending SAM and diverting nicotinamide away from the NAD+ salvage pathway

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The compound contains: A heterocyclic core structure Multiple functional groups that enhance its binding capabilities A molecular weight optimized for drug-like properties These structural characteristics of SLU-PP-332 play a significant role in its interactions with biological targets and its overall pharmacological profile

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The SEMA of c-MET is the only domain involved in the direct interaction with HGF

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