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Currently undergoing clinical trials is retatrutide, a triple agonist of the GLP-1, GIP and glucagon receptors, which has produced weight loss of 24% 30
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Specialized athletic testing (WADA protocols) can detect certain growth hormone secretagogues, but this is not relevant for most patients
Dual GLP-1/GIP (tirzepatide 15 mg) delivers ~21%
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Both prevention and reduction of atherosclerosis have been observed in diverse rodent models exposed respectively to numerous GLP-1R agonists
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