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a molecule that simultaneously activates three metabolic receptors: GLP-1, GIP and the glucagon receptor

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Owing to its -helical binding conformation, GLP-1 stroke us as both a good model for testing -helix mimicry with oligourea foldamers and a relevant pharmaceutical target

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Experimental studies describe BPC-157 as interacting with signaling pathways linked to vascular endothelial growth factor receptors and nitric-oxidemediated endothelial signaling [1][6][11]

doi: 10.1016/j.tplants.2005.03.002 22 KumarK.DeyA.RoseM