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The safety data comes primarily from animal studies, with human use data coming from clinical practice rather than formal trials

The short answer: In most cases, yes

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Chemotherapy-Induced Polyneuropathy Chemotherapy-induced peripheral polyneuropathy affects up to 80% of patients treated and constitutes a series adverse event, the occurrence of which may require anti-cancer therapy dose adjustment [69]

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Cardiologo per il controllo dei fattori di rischio cardiovascolare