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However, such methods have been either unpractical and/or unsuccessful
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Nevertheless, over the last twenty years there has been an increasing number of clinical studies evaluating nose-to-brain delivery as a novel option for the treatment of neurodegenerative and neurological diseases
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Mortensen A, Aguilar F, Crebelli R, Di Domenico A, Dusemund B, Frutos MJ, et al: Re-evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives
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