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Monitoring and safety: We routinely check glycemic markers (fingerstick patterns, HbA1c), counsel about GI side effects, and monitor for signs of pancreatitis or gallbladder issues
This is especially important when daily GLP-1 regimens face a high risk of discontinuation within just 120 days
You may also have irritation or itching in the anal region
Tirzepatide is usually injected once weekly
Starting a GLP-1RA appears associated with reduced risk of incident alcohol use, and possibly reduced opioid, cocaine, and nicotine use
Changes tend to show up quietly and build over time rather than all at once
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