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Obesity-related HFpEF is the most common phenotype of this disorder 3,9 , and its emergence is causally related to the growing burden of cardiovascularkidneymetabolic disorders observed worldwide 4

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Moreover, administering ghrelin intravenously in participants with alcohol-dependence increased the anticipatory alcohol signal in the amygdala during alcohol clamp, and modulated an anticipatory food signal in the medial orbitofrontal cortex and NAc differentially, depending on alcohol consumption (Farokhnia et al., 2018)

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