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Chronic Disease Management Glutathione deficiency may be caused by HIV/AIDS, cancer, type 2 diabetes, Parkinson's disease, or hepatitis conditions that both deplete glutathione and are worsened by its depletion

Beyond about 200mg, absorption drops dramatically, and excess is excreted

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However, the antioxidant benefits, reduction of oxidative stress, and improved natural killer cell function require that reduced glutathione is absorbed into the cells, not just in the plasma

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