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AOD9604 in Intra-Articular Cartilage Research In a 32-rabbit controlled study, weekly intra-articular injections of AOD9604 at 0.25 mg were evaluated over 47 weeks in a collagenase-induced osteoarthritis model
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There is a lack of long-term effects data, including concerns about abnormal cell growth and the need for ongoing evaluation and monitoring
PTD-DBM is applied topically, limiting its effects to the treatment site
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Months 3-6: Full protocol optimization
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