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Both medications are highly effective when prescribed correctly and managed with proper oversight

Once inside the body, NMN is quickly converted into active NAD+

Strategic Fit: Post-merger, Pfizers pipeline (on paper) now included the three GLP-1/amylin candidates

Using a 90-degree angle without sufficient tissue depth risks injecting into muscle

Phase 3 monotherapy available Feature Expected GI burden Cagrilintide + Retatrutide Very high CagriSema (Cag + Sema) High Retatrutide Alone High Feature Dysesthesia risk Cagrilintide + Retatrutide Yes (retatrutide component) CagriSema (Cag + Sema) No Retatrutide Alone Yes Feature Injections per week Cagrilintide + Retatrutide 2 (separate) or 1 (pre-blend) CagriSema (Cag + Sema) 1 or 2 Retatrutide Alone 1 Feature Regulatory status Cagrilintide + Retatrutide Neither approved

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