Limitations include the lack of a placebo group, the fact that more than 80% of participants were of White ethnicity, and that tirzepatide was only assessed in people with type 2 diabetes and CVD
The active compound in milk thistle, silymarin, works by increasing the production of glutathione in the liver
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This research shows us that they might be useful to manage food preoccupation and binge eating, but not in their current form. Although this study only featured the data from one person taking tirzepatide, it provides compelling data about how GLP-1 and GIP inhibitors alter electrical signals in the brain, said co-first author Wonkyung Choi, a PhD candidate in Halperns lab