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The absence of substantial modern follow-up research may reflect limited reproducibility, insufficient clinical benefit, pharmaceutical development challenges, or reduced scientific interest relative to newer sleep therapeutics [1617]

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Long-term follow-up studies are needed to assess durability of therapeutic effects and to identify any delayed adverse effects or complications that might not be apparent in shorter-term investigations

Abstract Introduction: A recent study reported a favorable effect of vitamin B12 injections/oral folic acid support in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients

68 weeks (trial-length) 68 syringes Pre-blended