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More clinical research and experiments in terms on antioxidant therapy, especially in deciding optimal drug dosages and treatment efficacy, stay pivotal for future investigations ( Above all, this review thoroughly summarizes the function of oxidative stress in periodontitis and discusses how antioxidants, by inhibiting oxidative stress, are applied in its treatment

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10.6091/ibj.1398.2015 141

additionally, a domain-specific assessment using the Cochrane Risk of Bias Tool (RoB 2) was also conducted and reported in Table 3 to provide a comprehensive appraisal

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