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CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

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However, overactivation of MCs can cause excessive release of chemical messenger molecules which trigger local and systemic effects, such as: increased permeability of blood vessels causing inflammation and swelling contraction of smooth muscle generating stomach cramps and heart palpitations increase mucous production triggering congestion, sneezing, etc

Assi, R, Benton CB, Al Rawi A, Chamoun K, Wang F, Pierce S, Patel KP, Hamilton BK, DiNardo CD, Garcia-Manero G, Kantarjian HM, Kadia T

One possible side effect is liver damage, although this is uncommon