According to the World Health Organization (WHO), approximately 890 million adults were living with obesity in 2022, while the International Diabetes Federation (IDF) estimated that 589 million adults aged 2079 years were living with diabetes globally in 2024, with the number expected to reach 853 million by 2050
For compounded semaglutide made in pharmacies that conduct rigorous stability testing, it may last up to 120 days in the fridge from the day it was compounded
Absolute contraindications include a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), as well as severe allergic reactions to its components
Additionally, its ability to improve insulin sensitivity and regulate adipose tissue inflammation makes it an attractive candidate for managing metabolic disorders beyond diabetes, such as non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome
10.1016/j.ecoenv.2014.11.008 92 ShahA
PMID: 258 WeaverBA