Apply light pressure with clean gauze if needed, but do not rub the area
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ADAMTS-13 regulates VWF function by cleaving it at the central A2 domain, thereby reducing its prothrombogenic potential and repressing thrombosis-induced inflammation through downregulation of P-selectin (80, 81)
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doi: 10.1182/blood-2018-02-831982 Nat Commun