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Despite these findings, it remains unclear whether OS is a primary factor in the development of PCOS or a secondary consequence of hyperglycemia, insulin resistance, and associated cardiovascular and necrotic complications in these women (124, 132)

Figure 4 5 Bench to bedside: fatty acid metabolism modulation for gout therapy 5.1 Regulation of lipolysis and fat synthesis 5.1.1 PPAR agonists PPAR utilizes both exogenous and endogenous FAs as substrates to promote lipogenesis and lipid synthesis

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