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When considering study drug discontinuation or use of rescue medication (trial product estimand results), the weight loss resulting from the use of oral semaglutide was up to 5 kg, while that associated with other active comparators ranged from 0.8 to 3.8 kg, and that associated with placebo ranged from 0.1 to + 0.6 kg [35,36,37,38,39,40]

2 For breast cancers, increased BMI is an independent risk for cancer recurrence and poorer overall survival

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Through Willow, compounded tirzepatide follows the standard tirzepatide dosing schedule

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