Continuous GLP-1RA use for three years was associated with the greatest reduction in MACE risk compared with sulfonylureas, whereas interruptions and discontinuations were associated with a progressive attenuation of this protective effect, with risk estimates in some scenarios approaching those of the comparator group
Move companies from startup to infrastructure They push companies to build real EHR integrations, insurance contracts, provider networks, fulfillment logistics, and employer channels
Refrigerate unused GLP-1 medication (36F to 46F [2C to 8C]), but not near the cooling element
doi: 10.1016/j.biopsych.2026.05.002 10.1016/j.biopsych.2026.05.002
The amount of sag depends on internal resistance, load level, and state of charge
These results, allied to recent meta-analyses from limited clinical trial data, underscore the need for a dedicated cardiorenal outcome trial to obtain direct evidence for the (cardiorenal) benefits and risks of SGLT2 inhibitor and GLP-1 RA combination therapy