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1 Further, those living with T2DM have a large array of therapeutic options for controlling blood glucose beyond exogenous insulin, and more opportunities exist for evaluating the CV safety of therapies in this patient population
Tablets 8.3.3
FDA Crackdown on Compounded GLP-1s (Regulatory): On February 6, 2026, the FDA announced a formal intent to restrict the use of active pharmaceutical ingredients (APIs) for non-approved compounded GLP-1 drugs, targeting "mass-marketed" alternatives from companies like Hims & Hers as the national supply of brand-name versions stabilized
Metformin has a boxed warning for lactic acidosis, a rare but potentially life-threatening buildup of lactic acid
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