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Nobuoka A, Takayama T, Miyanishi K et al (2004) Glutathione-S-transferase P1-1 protects aberrant crypt foci from apoptosis induced by deoxycholic acid

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management in adults

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The Endocrine Society research showed that men who lost 10% of body weight with GLP-1 medications saw their normal testosterone proportion rise from 53% to 77%, without any testosterone supplementation

Stimulant laxatives (senna, bisacodyl) should be reserved for occasional breakthrough constipation rather than daily management