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With a 30-minute half-life on the CJC-1295 (No DAC) side, spacing the two several hours apart means the GHRH signal has largely cleared before the ghrelin signal is working and the supra-additive effect is what you lose

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Importantly, GHK-Cu did not negatively impact cell proliferation or NO secretion in these macrophages, suggesting its protective effects were specific to inflammatory pathways rather than general cytotoxicity [1]