GLU.QDS displayed superior hemolysis stability (IC = 7.17 g/mL) and -amylase inhibition (IC = 4.73 g/mL)
Combining this approach with CRISPR screening, we identified SLC33A1 as the major ER GSSG exporter in mammalian cells
For each well, the fold change in luminescence relative to the initial luminescence was measured and reported in a log 2 scale as the number of cell doublings
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In vitro studies often include compound stability analysis, redox response evaluation, and comparative testing under varied laboratory conditions