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3 This process initiates with danger-signal-triggered immune system activation: CD8 T cells recognize melanocyte surface antigens and launch cytotoxic attacks, while simultaneously secreting interferon-gamma (IFN-)

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The main difference between eryptosis and senescence of RBCs is the time constant of clearance, and it was shown that ionomycin-treated eryptotic mouse cells are cleared within minutes, whereas the clearance process of normal, healthy mouse erythrocytes takes several days [417]

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