They also can reduce the risk of vessel leakage and retinal scarring
However, this same mechanism that makes them effective for weight loss can trigger gastrointestinal side effectsmost commonly diarrheain approximately one in four users during the first weeks of treatment
Molecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisal
These medications also slow gastric emptying , which helps moderate post-meal blood glucose spikes and promotes satiety, leading to reduced calorie intake and weight loss
This evolving landscape is further complicated by the body positivity movement, which challenges traditional pathologizing frameworks and advocates for a broader appreciation of body diversity and health beyond BMI
Zepbound (approved November 2023): for chronic weight management in obesity, or in overweight with a related condition, and since 2024 additionally for obstructive sleep apnea