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doi: 10.1371/journal.pone.0021106

10.1016/j.bbabio.2010.03.005 Biochim

if a patient is on blood pressure-lowering drugs (such as beta blockers, alpha-1 blockers, or vasodilators), niacinamide injections could lead to an additive drop in blood pressure

Melasma is characterized by symmetrical, blotchy, brownish facial pigmentation caused by overproduction of melanin by the pigment-producing cells melanocytes