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A study examining b.End.3 cells exposed to high glucose levels in vitro demonstrated a dose-dependent increase in permeability, with increased HIF-1 and decreased expression of the TJ proteins, ZO-1 and occludin (Yan et al., 2012)

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[96] observed a mild improvement in LV ejection fraction in ST-segment elevation MI patients who were not necessarily diabetic

While glutathione itself functions as an antioxidant and cellular protector, it also influences inflammatory signaling pathways including the NF-B pathway, which regulates the expression of numerous inflammatory mediators

Many diseases of the brain (for example, Alzheimer disease and stroke) are heterogeneous with a wide range of aetiological subtypes derived from multiple risk factors

R., Gruenig, B