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David Sinclair, Life Biosciences co-founder (Jemal Countess/Getty Images for TIME) April 8, 2026 08:00 AM EDTUpdated 08:41 AM Financing Startups Cell/Gene Tx David Sinclair startup raises $80M for clinical test of anti-aging gene therapy Ryan Cross Senior Science Correspondent A startup developing a one-time treatment that is intended to rewind the clock on dying cells announced a major influx of funding
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Circadian pathway Modulation of the circadian rhythm Regulates sleep-wake cycles Normalizes sleep disorders Effects lasting several days Opioid route Endogenous opioid system Pain perception module Blocked by naloxone Supports weaning management Stress response Hypothalamic-pituitary-adrenal axis Reduces stress responses Reduces cortisol secretion Improves stress management Unique biological properties Unlike most peptides, DSIP freely crosses the blood-brain barrier and can be absorbed by the intestine without enzymatic degradation
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Gkogkolou P, Sarna M, Sarna T, Paus R, Luger TA, Bhm M
