Journal of Controlled Release
Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models
Administered via subcutaneous injection or oral capsule (for GI-specific applications)
Topical GHK-Cu data does not establish the effect of injected GLOW or KLOW
CJC-1295 / Ipamorelin results timeline What research describes changing over weeks
Nutrition (Burbank, Los Angeles County, Calif)