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J Clin Endocrinol Metab (2019) 104:45949

The structure of liraglutide (a structurally distinct analog of GLP-1RA) was found to be unfavorable for co-formulation with SNAC on account of its stronger membrane-binding properties, which reduced transcellular passage, as well as its greater tendency to oligomerize, which countered the monomerizing effects of SNAC [56]

For many clinicians, GLP-1 therapies represent one of the most meaningful advances in obesity treatment in decades

This was associated with slower decline in cognitive function

The two most prevalent side effects are nausea and constipation