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Introduction Cell death has long been recognized as a characteristic of malignancy [1, 2]

Clinical trials showed significant results over 72 weeks when combined with lifestyle changes

Clinical trials show average 1215% body weight reduction in non-exercising patients over 6 months, with some individuals reaching 20% or more

Weight loss also tends to stop once patients lose about 15% of their body weight. Patients in the United States are filing lawsuits against Novo Nordisk and other drug companies, alleging insufficient warning labels on Rybelsus and similar products

By six months, most people have regained a measurable portion of their lost weight, and by one year, the regain is typically substantial

nausea or abdominal distress