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That said, if youve tried holistic solutions like adjusting your diet or being more physically active, and youre still not losing weight, it might be worth talking to your healthcare provider

The current evidence does not support a direct mechanism by which semaglutide would cause joint inflammation or damage

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Acknowledgements This paper was funded by grants from the National Natural Science Foundation of China (82070588, 82370577), National Key R&D Program of China (2023YFA1800801)