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Patients should be offered this alternative after an informed discussion on the advantages and disadvantages of both treatment options. oral vitamin B12 is an effective alternative to vitamin B12 IM injections Cochrane Review

Your haematologist will advise on how long you need to keep taking the injections

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This serves two purposes: receptor sensitivity maintenance (continuous stimulation can lead to downregulation) and allowing you to assess your baseline before adding another layer of intervention

Circular dichroism spectroscopy data indicated that Vit B12 delays the conformational transition of SN into -sheet-rich structures, with a particular influence on the parallel -sheet conformation

Some are already widely used as medicines