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Between 2020 and 2024, sleeve gastrectomy, long the dominant procedure, fell from 64% of all surgeries to 58%

Marso SP, Holst AG, Vilsbll T

Lasers Med Sci

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Whilst one meta-analysis of 24 RCTs found a decrease in the pro-inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6), 15 the other (based on 28 studies) found a decrease in interleukin-8 (IL-8) when pooling all data and a decrease in IL-6 in a subset of studies using a dose of 1200 mg NAC per day or less, but no difference in CRP

The main consideration is that both can cause nausea, particularly in the early weeks