These CAFs uptake OxLDL and activate the PPARG-FABP4 axis, leading to ANGPTL4 secretion that promotes CD8+ T cell exhaustion
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In addition, acetaldehyde is highly reactive and capable of adducting proteins and lipids that, in turn, initiate a series of deleterious cellular events
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QCN) is a widely distributed plant-derived flavonoid found in apples, onions, tea, nuts, seeds, and numerous other botanical sources 9