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Consistently, here, we have shown that Hex is unable to upregulate BDNF in the absence of PPAR and that lentiviral overexpression of flPPAR , but not mutated Y464D-PPAR , restores Hex-mediated BDNF upregulation, highlighting an important role of Y464 of PPAR in neurotrophic function of Hex
10.1074/jbc.M404751200 280 YangY.LiuJ.-p.FangJ.-y.WangH.-c.WeiY.CaoY.et al (2019)
J Neuroimmunol 209(12):615
Fear often overshadows understanding, this breaks it down clearly
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