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The Framingham Offspring study found that 39% of the general population may be in the low normal + deficient B12 blood level range
If you're in a risk group reduced food intake on GLP-1s, plant-based diet, long-term metformin or PPI use, over 50 and fatigue is dragging you down, checking your B12 is one of the highest-ROI moves you can make
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Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement
This means that it may help reduce the risk of developing dementia or memory loss
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That's where treatments like injectable B12 for humans come into play
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