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The bigger your meal size, the more acid that needs to be produced, moreover, pressurizing the lower esophageal sphincter will cause it to open, allowing stomach contents to leak back up into the esophagus, causing heartburn
Johnson DA
Clinical Pearls for Practice Early use lowers long-term CV risk even if baseline A1C is near target
Semaglutide remains widely available in Canada through prescription, though supply shortages have affected access periodically
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