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BPC-157 does not directly improve sleep through hormonal mechanisms, though reducing chronic pain or inflammation may indirectly improve sleep quality in patients whose sleep is disrupted by physical discomfort

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doi: 10.3390/jcm10030441 20 McIlroyGDSuchackiKRoelofsAJYangWFuYBaiBet al

Collectively, these findings demonstrate that psychological trauma initiates a cascade of interconnected MGBA disruptions in PTSD, encompassing HPA axis dysregulation, microbial dysbiosis, compromised gut barrier integrity, chronic inflammation and neurotransmitter imbalances across serotonergic, dopaminergic, and GABAergic systems