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Tirzepatide is a glucose-dependent insulinotropic polypeptide/GLP- 1 dual receptor agonist (GIP/GLP- 1 RA) and in the Phase 3 SURMOUNT- 1 trial, tirzepatide 5 mg, 10 mg and 15 mg produced mean weight reduction from baseline to week 72 of 15,0%, 18.5% and 20.9%, respectively, versus 2.4% for placebo

Endogenous Metabolite Regulation: Certain GSTs are involved in the metabolism and regulation of endogenous compounds, such as bile acids and hormones, contributing to metabolic balance

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Additionally, it stimulates collagen synthesis, improving skin elasticity and firmness