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Eer baz tmrlerde GLP-1R ekspresyonu daha iyi sakalmla ilikiliyse, GLP-1 sinyallemesinin yalnzca sistemik metabolik etkilerle deil, tmr veya tmr mikroevresi dzeyinde de rol oynayabilecei hipotezi glenir

[9] [2] This mechanism, whilst highly effective for glycaemic control, directly impacts gastrointestinal function