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The "U-100" marking means that the 1ml capacity is divided into 100 small increments, or "units." This fine measurement capability is what allows for precise dosing of micrograms (mcg)

However, the natural GLP-1 has a very short half-life, lasting only 1-2 minutes in the bloodstream

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Niacin can produce a variety of GI effects, such as nausea/vomiting, abdominal pain, diarrhea, bloating, dyspepsia, or flatulence, when taken in large doses

PMID: 41844462 Ahmed F et al