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Studies on the mechanism of haloacetonitrile-induced gastrointestinal toxicity: interaction of dibromoacetonitrile with glutathione and glutathione-S-transferase in rats

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Similarly, smoking introduces harmful chemicals that produce free radicals, leading to further oxidative stress and inflammation

By decreasing malondialdehyde, ROS levels and inhibiting ferroptosis via the p53/SLC7A11 axis, HSDL2 knockdown was found to promote CCA progression

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You cannot reasonably expect a positive outcome with the primary treatment if you do not do all in your power to maximize the chances of success