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More than ever, its management demands a multidisciplinary approach, not only to ensure effective treatment but also to prevent long-term complications and support overall quality of life [16]

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162 Moreover, restricted intake of dietary protein or methionine/cystine has been shown to modify the infiltration and tumoricidal capacity of TAMs, leading to a significant increase in tumor-infiltrating CD8 + T cells and a decrease in the number of infiltrating MDSCs

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