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Obviously, it may be unclear which one of the parts of peptide + carrier complex would be responsible for the activity (for review, see Urist, 1996)
Recent developments underscore the relevance of GLP-1R agonists in addressing the complex interplay of cardiovascular-kidney-metabolic (CKM) syndrome, microvascular dysfunction, and metabolic-associated steatohepatitis (MASH)
Other chemotherapy agents, including 5-FU and its prodrug, capecitabine (Xeloda), cisplatin, paclitaxel, and docetaxel, can also cause cardiotoxicity (Molinaro 2015
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Gastroenterology 2005
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