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In the plasma membrane, CoQH2 can be produced from ubiquinone (oxidized CoQ) by ferroptosis suppressor protein 1 (FSP1) [16]
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Transactivation of NRF2 in KO livers was further supported by constitutive induction of NRF2 target genes, including Gclc , metallothionein I ( Mt1 ) and heme-oxgenase 1 ( Hmox1) (Fig
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Sustained elevation: IGF-1 levels remained improved throughout the treatment period, suggesting consistent pituitary responsiveness without rapid desensitization
When the tumor volumes reached approximately 100 mm 3 , twenty female BALB/c nude mice bearing 143B tumors were randomly assigned into four groups
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