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Detectable medication levels can linger for five to seven weeks after the last injection
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In contrast to those in other tissues, the membrane of the barrier-type brain endothelial cell (BEC) is continuous and sealed by extra intercellular junctional structures, such as tight junction protein zonula occludens-1 (ZO-1), claudins-1, -3, -5, and -12, and occludin
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