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At the time of diagnosis of clinical ASCVD in a patient with T2D on a drug regimen that does not include a GLP-1 RA or an SGLT-2 inhibitor with demonstrated cardiovascular benefit

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Neuroscience and biobehavioral reviews

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Sub-diaphragmatic resection of the vagus nerve, with surgical completeness confirmed by fluorogold label (Figure 2C) and lack of weight gain (Supplementary Figure 2), had no effects on GLP-1-induced acute activation of PKA in the brain (Figures 2D,E)

cDNA was subsequently generated by TaKaRa PrimeScript RT reagent Kit (Takara, RR037A)