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Every Blue Cross Blue Shield company, including Anthem companies, operates independently

Do not use nutritional supplements to replace a full and balanced diet

For those with severe obesity or obesity-related conditions, our team works alongside experienced bariatric specialists who can discuss additional options when appropriate so medical and surgical approaches can work together as part of a long-term strategy

High levels of leptin, which are common in individuals with obesity due to leptin resistance, fail to properly signal satiety, leading to continued food intake and reduced energy expenditure [32]

Further investigation of differential gene expression in -1 cells revealed that the most highly upregulated transcripts in response to liraglutide treatment were INS and IAPP (Figure 4, A and B, and Supplemental Figure 4A

DIRECTIONS FOR FUTURE RESEARCH The clinical use of GLP-1RAs and dual GIP/GLP-1RAs has risen sharply in recent years, driven by their proven efficacy in managing T2DM and obesity